Amanda Raimer publishes paper in Disease Models & Mech.
Amanda Raimer (Greg Matera lab) published an article titled “Temperature-sensitive spinal muscular atrophy-causing point mutations lead to SMN instability, locomotor defects and premature lethality in Drosophila” in Disease Models and Mechanisms. (DOI: 10.1242/dmm.04330) Image: Temperature-sensitive protein stability in SMN Tudor …
Meng Cheng (Yue Xiong lab) published a paper titled “Discovery of potent and selective epidermal growth factor receptor (EGFR) bifunctional small-molecule degraders” in J. Medicinal Chemistry (DOI: 10.1021/acs.jmedchem.9b01566). Image: Hi-C maps showing signal in wild-type and Wiz deletion cells (see …
Megan Justice (Jill Dowen lab) published a paper titled “A WIZ/Cohesin/CTCF complex anchors DNA loops to define gene expression and cell identity” in Cell Reports (DOI: 10.1016/j.celrep.2020.03.067). Image: Hi-C maps showing signal in wild-type and Wiz deletion cells (see article …
Spencer Nystrom and Matt Niederhuber (Dan McKay lab) published a paper titled “Expression of E93 provides an instructive cue to control dynamic enhancer activity and chromatin accessibility during development” in Development (DOI: 10.1242/dev.181909). Image: Composite image of precocious activity of …
Meng Cheng publishes paper in Journal of Medicinal Chemistry
Megan Justice publishes paper in Cell Reports
Spencer Nystrom and Matt Niederhuber publish paper in Development