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Nate Diehl publishes paper in J. Biological Chemistry

January 3, 2022

Nate Diehl (Channing Der lab) published an article titled “The KRAS-regulated kinome identifies WEE1 and ERK coinhibition as a potential therapeutic strategy in KRAS-mutant pancreatic cancer” in Journal of Biological Chemistry (DOI:10.1016/j.jbc.2021.101335). . Image: Inhibition of WEE1 + ERK1/2 arrests growth of …

Jack Sanford publishes paper in BMC Molecular and Cell Biology

October 12, 2021

Jack Sanford (Yanping Zhang lab) published an article titled “MDMX is essential for the regulation of p53 protein levels in the absence of a functional MDM2 C-terminal tail” in BMC Molecular and Cell Biology (DOI:10.1186/s12860-021-00385-3). Image: Protein blots showing that DNA …

Spencer Nystrom publishes paper in PLOS Computational Biology

October 12, 2021

Spencer Nystrom (Dan McKay lab) published an article titled “Memes: A motif analysis environment in R using tools from the MEME Suite” in PLOS Computational Biology (DOI: 10.1371/journal.pcbi.1008991). Image: Representative plots generated by Memes. (see article for details; click to enlarge). …

Nila Pazhayam and Carolyn Turcotte publish review of meiotic crossover patterning

August 10, 2021

Nila Pazhayam and Carolyn Turcotte (Jeff Sekelsky lab) published a review of genome-wide meiotic crossover patterning processes in Fronteirs in Cell and Developmental Biology (DOI: 10.3389/fcell.2021.681123).  Image: Suppression of crossovers in peri-centromeric regions (click to enlarge; see article for details). Please … Read more