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Tamara Roman publishes paper in American Journal of Human Genetics

December 11, 2015

Tamara Roman (Karen Mohlke lab) published an article titled “Multiple hepatic regulatory variants at the GALNT2 GWAS locus associated with high-density lipoprotein cholesterol” in American Journal of Human Genetics 97: 801-15. Image: Transcription factor CEBPB binds differentially to the alleles …

Erin Borchardt publishes paper in RNA

December 2, 2015

Erin Borchardt (Aravind Asokan lab) published an article titled “Controlling mRNA stability and translation with the CRISPR endoribonuclease Csy4” in RNA 21: 1921-30. Image: effects of wild-type (top) and mutant (bottom) Csy4 on gene expression; see article for details.   …

Marni Siegel publishes paper in Molecular Cancer Therapeutics

December 2, 2015

 Marni Siegel (Carey Anders and Chuck Perou labs) published an article titled “Efficacy of carboplatin alone and in combination with ABT888 in intracranial murine models of BRCA-mutated and BRCA-wild-type triple-negative breast cancer” in Molecular Cancer Therapeutics 14: 920-30. (Image: expression …

Mira Pronobis publishes paper in eLife

October 2, 2015

Mira Pronobis (Mark Peifer lab) published an article titled “A novel GSK3-regulated APC:Axin interaction regulates Wnt signaling by driving a catalytic cycle of efficient β-catenin destruction” in eLife doi: 10.7554/eLife.08022. (Image: Superesolution microscopy (SIM) showing macromolecular complex between axin (magenta) …