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Meng Cheng publishes paper in Journal of Medicinal Chemistry

April 27, 2020

Meng Cheng (Yue Xiong lab) published a paper titled “Discovery of potent and selective epidermal growth factor receptor (EGFR) bifunctional small-molecule degraders” in J. Medicinal Chemistry (DOI: 10.1021/acs.jmedchem.9b01566). Image: Hi-C maps showing signal in wild-type and Wiz deletion cells (see …

Megan Justice publishes paper in Cell Reports

April 21, 2020

Megan Justice (Jill Dowen lab) published a paper titled “A WIZ/Cohesin/CTCF complex anchors DNA loops to define gene expression and cell identity” in Cell Reports (DOI: 10.1016/j.celrep.2020.03.067). Image: Hi-C maps showing signal in wild-type and Wiz deletion cells (see article …

Spencer Nystrom and Matt Niederhuber publish paper in Development

April 12, 2020

Spencer Nystrom and Matt Niederhuber (Dan McKay lab) published a paper titled “Expression of E93 provides an instructive cue to control dynamic enhancer activity and chromatin accessibility during development” in Development (DOI: 10.1242/dev.181909). Image: Composite image of precocious activity of …

Juan Carvajal Garcia publishes article in PNAS

April 12, 2020

Juan Carvajal Garcia (Dale Ramsden lab and Jeff Sekelsky lab) published an article titled “Mechanistic basis for microhomology identification and genome scarring by polymerase theta” in Proceedings of the National Academy of Sciences (DOI: 10.1073/pnas.1921791117).  Image: Model for generation of …