Genomics

Mechanisms of epigenetic regulation by long noncoding RNAs

Plant disease resistance using Arabidopsis, innate immunity and cell-death control. Plant genomics. Bacterial pathogenesis and genomics, type III secretion systems

Three-dimensional genome architecture and gene regulation in development and disease

Regulation of fat metabolism during development, aging, and disease

Molecular, cellular and bioinformatic dissection of the formation and function of transcriptional enhancers in cancer

Genomic DNA transfer, drug-gene delivery and nanomedicine

Integrative genomic characterization of cancer and precancer

Genetics and genomics of environmentally-induced asthma

Mammalian genetics; epigenetics; genomics

developmental genomics; regulation of gene expression

Systems genetics, genetics of complex traits, meiotic drive.

Genomic and molecular classification of human tumors to guide therapy

Characterization and functional studies of dynamic DNA looping during monocyte differentiation in healthy individuals and in human disease, using genomics, genome editing, and bioinformatics.

Regulation and function of altered chromatin remodeling complex activity.

The Rau lab utilizes populations of mice to study the transcriptomic and epigenomic landscape underlying cardiovascular disorders using a combination of wet and dry-lab techniques

Mechanisms of mitotic and meiotic recombination, double-strand break repair.

Genetics responses of immune cells to the gut microbiome; inflammatory bowel diseases (Crohn's disease, ulcerative colitis

Function and development of macrophages and brain microglia; regulation of inflammation and innate immune activation; genetic, genomic, cellular, and imaging approaches.

Roles of chromatin-modifying enzymes in developmental epigenetics and disease

Context Specific Functions of Long Noncoding RNAs.

Genetic influences on brain structure and development

Genetic mapping of complex behavioral traits